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![High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat : Nature : Natur]()
www.nature.comHigh-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat : Nature : NaturFigure 2: Naked mole-rat tissues contain high levels of HA. Mice and rats are standard animal models for cancer research due in part to their short lifespan and high incidence of cancer. However, these traits indicate that mice and rats have fewer antican瀏覽：1458 -
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日期：2024-04-19
1. FASEB J. 1992 Apr;6(7):2397-404. Hyaluronan. Laurent TC, Fraser JR. Hyaluronan (hyaluronic acid) is a high-molecular-mass polysaccharide found in the extracellular matrix, especially of soft connective tissues. It is synthesized in the plasma membrane ...
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日期：2024-04-23
Hyaluronan (also called hyaluronic acid or hyaluronate or HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in that it is nonsulfated, forms in ...
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日期：2024-04-24
The biological functions of hyaluronan are strongly depending upon its size. High molecular weight hyaluronan polymers ( Da) are space filling, antiangiogenic, and immunosuppressive; medium size hyaluronan chains (between 2 × 10 4 –10 5 Da) are involved i...
Microbial Cell Factories | Full text | Microbial production of hyaluronic acid: Current state, chall
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日期：2024-04-18
Hyaluronic acid (HA) is a natural and linear polymer composed of repeating disaccharide units of β-1, 3-N-acetyl glucosamine and β-1, 4-glucuronic acid with a molecular weight up to 6 million Daltons. With excellent viscoelasticity, high moisture retentio...
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日期：2024-04-22
Accumulation and turnover of extracellular matrix components are the hallmarks of tissue injury. Fragmented hyaluronan stimulates the expression of inflammatory genes by a variety of immune cells at the injury site. Hyaluronan binds to a number of cell su...
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日期：2024-04-19
Introduction Hyaluronic Acid (also called Hyaluronan and Hyaluronate) is a non-sulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is one of the chief components of the extracellular matrix....
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日期：2024-04-23
Veterinarni Medicina, 53, 2008 (8): 397–411 Review Article 399 3. Physicochemical and structural properties Hyaluronan, an extracellular matrix compo-nent, is a high molecular weight glycosamino-glycan composed of disaccharide repeats of N-acetylglucosami...
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日期：2024-04-20
6 Strauss et al The American Journal of Sports Medicine after 3 weekly injections of high-molecular-weight HA, the mean HA concentration in the synovial fluid of 27 patients had increased by 13% (P < .0008). By the 6-month fol-low-up, the HA concentration...
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