search:off target effect相關網頁資料

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日期:2024-05-20
Off-target effects arise when an introduced RNA has a base sequence that can pair with and thus reduce the expression of multiple genes. Such problems occur  ......
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日期:2024-05-21
2010年10月30日 ... RNAi实验中脱靶效应(Off-Target Effect),要想了解脱靶效应的由来以及如何有效的 避免脱靶效应,我们首先需要了解RNAi的机理....
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日期:2024-05-19
10 Dec 2013 ... Off-target mutagenesis is an emerging problem when inducing site-specific DNA breaks for genome editing. Cho et al. used high-throughput ......
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日期:2024-05-22
Hepatitis C virus-targeted shRNAs designed to include an internal loop two nucleotides away from the expected site of Dicer cleavage had reduced off-target  ......
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日期:2024-05-17
Caveat of RNAi in plants: the off-target effect. Senthil-Kumar M, Mysore KS. RNA interference (RNAi), mediated by short interfering RNAs (siRNAs), is one of the ......
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日期:2024-05-23
Here, we show that off-target effects of RGENs can be reduced below the detection limits of deep sequencing by choosing unique target sequences in the  ......
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日期:2024-05-24
A phenotype resulting from this knockdown of expression may inform about the function of the targeted gene. However, 'off-target effects' compromise the ......
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日期:2024-05-19
19 Nov 2013 ... An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all ......