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日期:2025-05-16
Rituximab, a chimeric murine/human monoclonal antibody, approved in the United States only for the treatment of refractory or relapsed B-cell lymphomas, reacts with the CD20 antigen (Figure 1). [8] It contains the complementarity determining regions of th...
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日期:2025-05-19
因此在1997年,Rituxan被研發出來當治療非何杰金氏淋巴瘤單株抗體新藥。在美國
,Rituxan是第一個被允許用來治療癌症 ......
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日期:2025-05-14
2011年6月30日 ... 關鍵字: 多發性硬化症、單株抗體 ... 代表藥物例如rituximab (Rituxan) 和basiliximab
(Simulect),嵌合單株抗體通常 ... 完全人類單株抗體(fully human mAbs,100%人類
,藥名以mumab 結尾) ......
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日期:2025-05-16
Mechanism of Action While rituximab has been used in the various indications, with the exception of lymphoma where the target lymphoma cells are actually eliminated by rituximab, it is not entirely clear that rituximab was responsible for the improvement ...
Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of pat
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日期:2025-05-19
1. J Clin Oncol. 1998 Aug;16(8):2825-33. Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program. McLaughlin P(1), Grillo-López AJ, Link BK, Levy R, Czuczman MS ......
Cytokine-release syndrome in patients with B-cell chronic lymphocytic leukemia and high lymphocyte c
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日期:2025-05-16
1. Blood. 1999 Oct 1;94(7):2217-24. Cytokine-release syndrome in patients with B-cell chronic lymphocytic leukemia and high lymphocyte counts after treatment with an anti-CD20 monoclonal antibody (rituximab, IDEC-C2B8). Winkler U, Jensen M, Manzke O ......
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日期:2025-05-17
This page contains brief information about rituximab and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials. ... Rituximab (rih-TUK-sih-mab) This page contains brief information about rituxi...
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日期:2025-05-19
Rituximab is available for intravenous (IV) use. How It Works Rituximab belongs to a group of medicines known as monoclonal antibodies. It is designed to recognize specific proteins that are found on the surface of some lymphoma cells. The monoclonal anti...