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日期:2024-09-16
In immunology, the CD3 (cluster of differentiation 3) T-cell co-receptor is a protein
complex and is composed of four ......
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日期:2024-09-19
TCRComplex.png. The T-cell receptor complex with TCR-α and TCR-β chains,
CD3 and ζ-chain accessory molecules....
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日期:2024-09-18
TCR-CD3 complex interaction plays an important role in mediating cell
recognition events. TCR engagement by ......
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日期:2024-09-19
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells)[1] that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen is of relatively low...
Immunotherapy with TCR-redirected T cells: comparison of TCR-transduced and TCR-engineered hematopoi
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日期:2024-09-15
1. J Immunol. 2014 Jan 1;192(1):206-13. doi: 10.4049/jimmunol.1202591. Epub 2013 Nov 29. Immunotherapy with TCR-redirected T cells: comparison of TCR-transduced and TCR-engineered hematopoietic stem cell-derived T cells. Stärck L, Popp K, Pircher H, Ucker...
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日期:2024-09-12
T cells or T lymphocytes are specialized lymphocytes distinguished by their TCR surface receptors. activation T reg: APC: apoptosis: B7-1: B7-2: CD8 +: CD28: CD80: CD86: costimulation: CTL: cytotoxic T lymphocytes: Fas-FasL: γδ T cells: granulysin: granzy...
Continuous requirement for the TCR in regulatory T cell function : Nature Immunology : Nature Publis
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日期:2024-09-17
Regulatory T cells help to keep adaptive immunity in check. Rudensky and colleagues show that these cells continuously require TCR signaling to maintain their cellular identity and homeostasis and to exert their suppressive ability....
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日期:2024-09-12
Gamma delta T cells (γδ T cells), represent a small subset of T cells that possess a distinct T-cell receptor (TCR) on their surface. Most T cells are αβ (alpha beta) T cells with TCR composed of two glycoprotein chains called α (alpha) and β (beta) TCR c...