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Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer : Abstract : Nat
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日期:2024-04-20
Top of page Abstract The existence of factors that stimulate blood vessel growth, thereby recruiting a neovascular supply to nourish a growing tumour, was postulated many decades ago, although the identification and isolation of these factors proved elusi...
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer : Article : Natu
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日期:2024-04-25
There is now a consensus that VEGFR2 is the major mediator of the mitogenic, angiogenic and permeability-enhancing effects of VEGF (for a more extensive review of the biological and signalling properties of the VEGF receptors, see Ref. 31). Although the ....
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日期:2024-04-20
VEGF (C-1) Antibody (C-1) sc-7269 ... VEGF Antibody (C-1) is a mouse monoclonal IgG 2a provided at 200 µg/ml raised against amino acids 1-140 of human VEGF recommended for detection of the 189, 165 and 121 amino acid splice variants of VEGF of mouse ......
Ang-2-VEGF-A CrossMab, a novel bispecific human IgG1 antibody blocking VEGF-A and Ang-2 functions si
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日期:2024-04-21
1. Clin Cancer Res. 2013 Oct 4. [Epub ahead of print] Ang-2-VEGF-A CrossMab, a novel bispecific human IgG1 antibody blocking VEGF-A and Ang-2 functions simultaneously, mediates potent anti-tumor, anti-angiogenic, and anti-metastatic efficacy. Kienast Y .....
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日期:2024-04-18
Western Blotting Protocol For western blots, incubate membrane with diluted primary antibody in 5% w/v BSA, 1X TBS, 0.1% Tween ® 20 at 4 C with gentle shaking, overnight. ... VEGF-C Antibody detects recombinant human VEGF-C protein at various ......
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日期:2024-04-22
VEGF (A-20) Antibody (A-20) sc-152 ... VEGF Antibody (A-20) is a rabbit polyclonal IgG provided at 200 µg/ml; also available as goat IgG provided at 200 µg/ml, sc-152-G...
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日期:2024-04-22
Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF),[1] is a signal protein produced by cells that stimulates vasculogenesis and angiogenesis. It is part of the system that restores the oxygen supply to tissue...
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日期:2024-04-24
The sequencing of the human genome is considered as one of the most important milestone of the century reached by the Life Science research community. Biologists have estimated the total number of genes at 25,000. Now, the annotated human genome ......