Histone Variants Enriched in Oocytes Enhance Reprogramming to Induced Pluripotent Stem Cells

Histone Variants Enriched in Oocytes Enhance Reprogramming to Induced Pluripotent Stem Cells

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日期:2025-05-07
Highlights • Two histone variants, TH2A and TH2B, are highly expressed in oocytes • TH2A/TH2B in oocytes contribute to activate the paternal genome after fertilization • TH2A/TH2B enhance OSKM-mediated reprogramming and are enriched on the X chromosome •...看更多