Differential regulation of the REGγ–proteasome pathway by p53/TGF-β signalling and mutant p53 in can

Differential regulation of the REGγ–proteasome pathway by p53/TGF-β signalling and mutant p53 in can

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日期:2026-04-23
To investigate whether p53 transcriptionally regulates REGγ, we co-transfected the REGγ-luc reporter into H1299 cells. Repression was observed when the reporter construct was co-transfected with different doses of p53 (Fig. 1b). Derepression of REGγ also ...看更多