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Cell Research - The critical role of CD133+CD44+/high tumor cells in hematogenous metastasis of live
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日期:2024-04-16
Top of page Abstract Metastatic hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide. However, the cell population responsible for its metastasis remains largely unknown. Here, we reported that CD133 + CD44 +/high defined a subgroup ...
Mouse model of carbon tetrachloride induced liver fibrosis: Histopathological changes and expression
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日期:2024-04-16
Fujii et al. BMC Gastroenterology 2010, 10:79 http://www.biomedcentral.com/1471-230X/10/79 Page 4 of 11 then incubated with appropriate secondary antibodies for 1 h at room temperature. An antibody directed against β-actin (Abcam) was used to verify equal...
The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like ce
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日期:2024-04-18
Fig. 1. Enrichment of the prostate CSC-like population under sphere-forming conditions. (A) Flow cytometry analysis showed significant enrichment of the CD133 + /CD44 + population under sphere-forming conditions compared with monolayer conditions for DU14...
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日期:2024-04-13
a, Representative magnetic resonance imaging (MRI) images from mice that received injection of DN, CD133 + /CD144 − or DP cells from primary GBM specimens. T2 sequences demonstrate infiltrative tumours except in the DN group. Tumours were hypercellular .....
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日期:2024-04-15
Identification of resident LSEC LRCs and progenitors. The LSEC expresses both CD31 and CD45 (8, 9). CD133 is a progenitor cell marker, and infusion of CD133 + cells from the BM repopulates the liver endothelium (8). We therefore used CD133 + CD45 + CD31 +...
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日期:2024-04-13
Nevertheless, although this in vivo selection technique has provided new insight into the cellular and molecular mechanisms that control site-specific metastasis, there are some disadvantages. Perhaps the principal drawback of in vivo selection is that it...
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日期:2024-04-18
Complete information for PROM1 gene (protein-coding), prominin 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium ... Function for PROM1 gene (According to 1 UniProtKB, Genatlas, LifeMap...
γ-Secretase Inhibitor, DAPT Inhibits Self-renewal and Stemness Maintenance of Ovarian Cancer Stem-li
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日期:2024-04-13
INTRODUCTION Ovarian cancer is the leading cause of death due to gynecological cancer [1]. Recurrence and chemoresistance are the major burdens in the treatment of ovarian cancer. Increasing evidence have shown that a small subset of cells, termed cancer ...