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日期:2025-06-04
1. Hepatology. 2013 Sep;58(3):995-1010. doi: 10.1002/hep.26394. Epub 2013 Jul 30. Hedgehog signaling pathway regulates autophagy in human hepatocellular carcinoma cells. Wang Y, Han C, Lu L, Magliato S, Wu T. Hedgehog (Hh) signaling plays an important ......
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日期:2025-06-05
Alteration of the Hedgehog pathway and cancer In recent years, it has become increasingly clear that the aberrant activation of the Hh signaling pathway can lead to cancer. Three basic models have been proposed for Hh pathway activity in cancer (Figure 2A...
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日期:2025-06-01
HH Biotech is a north India based Biotechnology Company. Presently, the company is focusing on two major areas mainly, BioIT (Cancer Drug Discovery, Systems Biology & Neuroinformatics) and Plant Biotechnology (Transgenic Plant Research)....
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日期:2025-06-08
Figure 2 | Models of Hh pathway activation in cancer. a | Type 1: loss-of-function mutations in Patched 1 (PTCH1; yellow star) or gain-of-function mutations in Smoothened (SMOH; blue star) lead to constitutive Hedgehog (Hh) pathway activation. b | Type 2:...
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日期:2025-06-08
The Executive Committee for GA Pathway to Language & Literacy met on Dec 7 th for their quarterly meeting. The Executive committee’s work is to create an essential roadmap for professionals, parents, and advocates. This roadmap – the ‘Path’- consists of a...
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日期:2025-06-08
ESCs (Embryonic stem cells) are Pluripotent cells derived from the ICM (Inner Cell Mass) of Blastocyst-stage embryos. These cells have two distinctive properties: an unlimited capacity for Self-renewal and Pluripotency. The capability for Self-renewal and...
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日期:2025-06-01
ATM (Ataxia Telangiectasia Mutated Protein) belongs to a family of Kinases that have sequence homology to PI3K (Phosphoinositide 3-Kinase). ATM is a key regulator of multiple signaling cascades which respond to DNA strand breaks induced by damaging agents...
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日期:2025-06-06
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