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日期:2025-05-06
The insulin and the IGF-1 pathway are closely intertwined. Both can bind the insulin receptor or the IGF receptor 1 (IGFR-1). IGF-2, on the other hand, can bind ......
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日期:2025-05-09
6 天前 - The consequent increase in IGF-IR mRNA stability. The regulation of IGF1 receptor expression by microRNA-100 in metatstatic and ......
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日期:2025-05-05
2008年11月21日 - As a key signaling component of IGF system, the IGF-1 receptor is the target of several investigational agents in clinical and pre-clinical ......
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日期:2025-05-10
The insulin and IGF-I receptors are members of the superfamily of receptor .... receptor).1 The Fugu rubripes genome45 has four genes encoding receptors from ......
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日期:2025-05-05
Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower ......
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日期:2025-05-07
IGF1R (insulin-like growth factor 1 receptor), Authors: Itay Bentov, Haim Werner. ... The cysteine-rich domain of the IGF1R is important for high-affinity IGF1 ......
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日期:2025-05-04
2008年3月4日 - Sequence analysis of the IGF1 and IGF1 receptor (IGF1R) genes of female centenarians showed overrepresentation of heterozygous mutations ......
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日期:2025-05-06
IGF-R1 signaling. The insulin-like growth factor system (IGF system) comprises two receptors: Insulin-like growth factor 1 receptor ( IGF-1 receptor ) and IGF-IIR ......