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Measuring and interpreting the selectivity of protein kinase inhibitors

Measuring and interpreting the selectivity of protein kinase inhibitors

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日期：2024-06-05
Many protein kinases have a catalytically active and inactive state. In the inactive state, it has been noted that the structures of the catalytic domain are more diverse. When the kinase is activated, often by phosphorylation on the activation loop (Fig....看更多

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