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日期:2025-05-07
Highlights • Two histone variants, TH2A and TH2B, are highly expressed in oocytes • TH2A/TH2B in oocytes contribute to activate the paternal genome after fertilization • TH2A/TH2B enhance OSKM-mediated reprogramming and are enriched on the X chromosome •...
Molecular Therapy - Efficient Reprogramming of Human Cord Blood CD34+ Cells Into Induced Pluripotent
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日期:2025-05-13
Top of page Abstract The reprogramming of cord blood (CB) cells into induced pluripotent stem cells (iPSCs) has potential applications in regenerative medicine by converting CB banks into iPSC banks for allogeneic cell replacement therapy. Therefore, furt...
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日期:2025-05-13
Induced Pluripotent Stem cells (iPSCs) are suitable for various purposes,
including: disease modeling; autologous cell ......
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日期:2025-05-13
22 Feb 2011 ... Self-renewal and pluripotency are defining properties of embryonic stem cells (
ESCs). They refer ......
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日期:2025-05-10
13 Feb 2014 ... Reprogramming of somatic cells into induced pluripotent stem (iPS) cells by the
OSKM transcription ......
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日期:2025-05-08
Here we discuss recent advances in generating induced pluripotent stem cells,
different reprogramming methods and ......
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日期:2025-05-09
Strategies to generate induced pluripotent stem cells. ... These protocols have
simplified the reprogramming strategy by employing polycistronic reprogramming
cassettes and flanking such polycistronic ......