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日期:2024-05-10
脫氧核醣核酸(英语:deoxyribonucleic acid,縮寫:DNA)又稱去氧核醣核酸,是一種生物大分子,可組成遺傳指令,引導生物發育與生命機能運作。主要功能是資訊儲存,可比喻為「藍圖」或「食譜」[1]。其中包含的指令,是建構細胞內其他的化合物,如 ......
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日期:2024-05-14
在過去,如SNP發生頻率佔對應的等位基因小於或等於1%,我們將這極少發生之等位基因產生變化之頻率稱之為mutation,意謂著SNP與mutation的差異為: 但依照現代生物資訊對演化較好的見解,此定義已不再需要。...
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日期:2024-05-14
Nucleotides are organic molecules that serve as the monomers, or subunits, of nucleic acids like DNA and RNA. The building blocks of nucleic acids, nucleotides are composed of a nitrogenous base, a five-carbon sugar (ribose or deoxyribose), and at least o...
Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive ca
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日期:2024-05-11
1. Cell. 2014 May 22;157(5):1088-103. doi: 10.1016/j.cell.2014.03.052. Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer. Cunningham JT, Moreno MV, Lodi A, Ronen SM, Ruggero D. Cancer cells must ......
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日期:2024-05-13
酵素 在這裡,我們將從酵素的命名、分類兩方面來介紹酵素,並詳述呼吸作用中扮演著重要角色的氧化還原酶。 一、酵素的命名 最初酵素命名,多數以-in、-ase、或-zyme 等字尾表示,例如 trypsin、pepsin、amylase、DNase、及 lysozyme 等。...
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日期:2024-05-10
The hardest part was finding the right reference number for the nucleotide sequence. Translation is controlled by various enzymes that recognize specific nucleotide sequences. Novelty at the nucleotide level comes from mutations. Many nucleotide differenc...
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日期:2024-05-11
A nucleotidase is a hydrolytic enzyme that catalyzes the hydrolysis of a nucleotide into a nucleoside and a phosphate. For example, it converts adenosine monophosphate to adenosine, and guanosine monophosphate to guanosine. Nucleotidases have an important...
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日期:2024-05-16
RNA聚合酶(簡稱RNAP,EC2.7.7.6)或稱核糖核酸聚合酶,是一種負責從DNA或RNA模板製造RNA的酶。RNA聚合酶是通過稱為轉錄的過程來建立RNA鏈,以完成這個工程。在科學上,RNA聚合酶是一個在RNA轉錄本3'端聚合核糖核甘酸的核苷轉移酶。...